Nanopore-based Fourth-generation DNA Sequencing Technology
نویسندگان
چکیده
Nanopore-based sequencers, as the fourth-generation DNA sequencing technology, have the potential to quickly and reliably sequence the entire human genome for less than $1000, and possibly for even less than $100. The single-molecule techniques used by this technology allow us to further study the interaction between DNA and protein, as well as between protein and protein. Nanopore analysis opens a new door to molecular biology investigation at the single-molecule scale. In this article, we have reviewed academic achievements in nanopore technology from the past as well as the latest advances, including both biological and solid-state nanopores, and discussed their recent and potential applications.
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The emergence of nanopores in next-generation sequencing.
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متن کاملCorrigendum to ‘Nanopore-based Fourth-generation DNA Sequencing Technology’ [GPB 144 (2015) – GPB 13/1 (4–16)]
http://dx.doi.org/10.1016/j.gpb.2015.05.001 1672-0229 a 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of Beijing Institute of Genomics, Chinese Academy of Scie Genetics Society of China. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Yanxiao Feng , Yuechuan Zhang , Cuifeng Ying , Deqiang Wang *, Chunlei Du ...
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